--- title: A Magnetic Bead-Free, Low-CapEx Workflow for Clinical-Scale CAR-T Manufacturing --- ![Webinar Landing Page Banner-1](https://info.akadeum.com/hs-fs/hubfs/Webinar%20Landing%20Page%20Banner-1.png?width=2000&height=400&name=Webinar%20Landing%20Page%20Banner-1.png "Webinar Landing Page Banner-1") [![Akadeum Life Sciences, Inc](https://info.akadeum.com/hs-fs/hubfs/Akadeum-Logo-Transparent-2.png?width=796&height=797&name=Akadeum-Logo-Transparent-2.png "Akadeum Life Sciences, Inc")](https://www.akadeum.com/) ## ![poster-tag](https://info.akadeum.com/hs-fs/hubfs/Akadeum_Poster-Tag_pink.png?width=169&height=53&name=Akadeum_Poster-Tag_pink.png) ## A Magnetic Bead-Free, Low-CapEx Workflow for Clinical-Scale CAR-T Manufacturing High-purity T cell isolation: Akadeum’s BACS Microbubbles reduced CD14+ and CD19+ cells to near-background levels and enriched CD3+CD56- T cells to over 90% of CD45+ cells, using gentle negative selection instead of magnetic beads or columns. Clinical-scale CAR-T output in seven days: Paired with BlueWhale Bio’s Synecta T1 activation and ScaleReady’s G-Rex 100M-CS, approximately 100 million starting T cells expanded 15 to 28-fold, producing 1.5 to 2.8 billion viable cells and 600 to 850 million CAR+ cells by Day 7. Simpler workflow, stronger cells: The functionally closed, bead-free process requires no cell manipulations after Day 0 and keeps capital costs low, while harvested cells were predominantly stem cell memory and central memory T cells, consistent with maintenance of a less-differentiated memory phenotype during expansion. **Download the poster** to see the full workflow and performance data 👉 ![Screenshot 2026-10-20 at 3.15.51 PM](https://info.akadeum.com/hubfs/Screenshot%202026-10-20%20at%203.15.51%20PM.png "Screenshot 2026-10-20 at 3.15.51 PM") ### Fill Out the Form to Download the Poster 734.707.1233 info@akadeum.com 674 S Wagner Rd Ann Arbor, MI 48103 [![Akadeum Life Sciences](https://info.akadeum.com/hs-fs/hubfs/Akadeum_February2019%20/images/logo-footer.png?width=80&height=85&name=logo-footer.png)](https://www.akadeum.com/) - - - - [Products](https://www.akadeum.com/products/) - [Partnerships](https://www.akadeum.com/partnerships/) - [Solutions](https://www.akadeum.com/technology/) - [Resources](https://www.akadeum.com/resources/) © 2024 [Akadeum Life Sciences](https://www.akadeum.com/)