--- title: Exceptionally Gentle Mouse B Cell Enrichment with Microbubbles Maintains Cell Health & Physiology description: Exceptionally Gentle Mouse B Cell Enrichment with Microbubbles Maintains Cell Health & Physiology. Download the app note now! --- [![Akadeum Life Sciences](https://info.akadeum.com/hubfs/Akadeum_February2019%20/images/logo.png)](https://www.akadeum.com/) # download the app noteExceptionally Gentle Mouse B Cell Enrichment with Microbubbles Maintains Cell Health & Physiology ## ![Download App Note MsBGentle](https://info.akadeum.com/hs-fs/hubfs/Download%20App%20Note%20MsBGentle.jpg?width=704&name=Download%20App%20Note%20MsBGentle.jpg) ## DOWNLOAD THE APP NOTE: Exceptionally Gentle Mouse B Cell Enrichment with Microbubbles Maintains Cell Health & Physiology Analysis of B cell function and regulation requires a highly purified population of unaltered B cells, but traditional separation technologies like magnetic bead-based sorting can be harsh on cells and ultimately produce less-than desirable results. *Buoyancy-Activated Cell Sorting (BACS) microbubble technology from Akadeum is a truly novel, non-invasive method for capturing unaltered cells in their natural physiological state.* Download this app note to see how researchers in laboratories across the country have used Akadeum's Mouse B Cell Isolation Kit to investigate critical aspects of B cell biology, including the distribution of B cell receptors (BCRs), the antigen-presenting capacity of B cells, and the differentiation potential of B cells following enrichment.  - BCR isotype distribution remains unchanged following microbubble-based enrichment - Microbubble isolation retains antigen presenting capacity of B cells - B cell differentiation potential is maintained through microbubble-based separation ***Akadeum's BACS microbubbles represent a breakthrough in next-generation gentle, innocuous cell isolation. *** ### [Contact](https://www.akadeum.com/contact/) [734.707.1233](tel:+1-734-707-1233) [info@akadeum.com](mailto:info@akadeum.com) [![Akadeum Life Sciences](https://info.akadeum.com/hubfs/Akadeum_February2019%20/images/logo-footer.png)](https://www.akadeum.com/) 674 S Wagner Rd Ann Arbor, MI 48103 © 2014-2022 [Akadeum Life Sciences](https://www.akadeum.com/)