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Mitigating Complexity in T-cell Manufacturing Through a Fully Integrated End-to-End Bioreactor Workflow

Efficient T-cell selection: Easily integrated BACS process with a flexible bag and rotating rocker design yielding ultra low-shear rapid cell purifications of 300-500 × 10^6 cells from one-tenth of a leukopak.
 
Robust expansion performance: Starting from 55 x 10^6 total viable cells, 6-8 x 10^9 fully activated, viable T cells were reproducibly generated from two independent donors.
 
Manufacturing efficiency: Sustained culture densities exceeding 7 × 1^6 cells/mL were achieved, supporting efficient production at clinically relevant scales.

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Scinus Poster_Akadeum JUL2026 (1)

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